목차
01장 수혈의 역사
1. 선조들의 피를 이용한 치료방법 ············································································ 3
2. 혈액 순환설과 수혈실험 ························································································· 3
3. 사람과 사람 사이의 수혈 ························································································ 4
4. 혈액형의 발견 및 수혈용 항응고제의 개발 ·························································· 4
5. 세계 최초의 혈액은행 및 연구업적 ······································································· 5
6. 혈액은행의 국내 현황 ····························································································· 6
◆ 학습문제 ···················································································································7
02장 면역혈액학
1. 면역계의 구성요소와 면역반응 ············································································11
2. 혈액형 항원과 항체 ···························································································· 23
3. 항원-항체 반응 ·································································································· 29
◆ 학습문제 ················································································································ 38
03장 혈액형
1. ABO 혈액형 체계 ······························································································· 45
2. Rh 혈액형 체계 ·································································································· 62
3. 기타 혈액형 ·········································································································· 69
◆ 학습문제 ················································································································ 77
􀁄 􀁐 􀁏 􀁕 􀁆 􀁏 􀁕 􀁔 04장 수혈을 위한 헌혈자 선택 및 채혈
1. 헌혈의 국내현황 ································································································· 87
2. 헌혈자 등록 ········································································································· 88
3. 헌혈자 선택 ········································································································· 91
4. 헌혈자 ·················································································································· 98
5. 채혈 ······················································································································ 99
6. 지정 헌혈 ·············································································································114
7. 자가 수혈 ··············································································································116
◆ 학습문제················································································································118
·
05장 혈액성분제제와 수혈요법
1. 혈액성분 수혈 ····································································································· 125
2. 혈액성분제제의 종류·························································································· 126
◆ 학습문제··············································································································· 154
06장 혈액 성분채집술
1. 성분채집술 정의 ····························································································· 159
2. 혈액 성분채집기의 원리 ················································································ 159
3. 혈액 성분채집기의 종류 ················································································ 160
4. 혈소판성분채집술 ·························································································· 160
5. 치료적 혈소판성분채집술················································································ 161
6. 혈장성분채집술 ······························································································· 163
7. 치료적 혈장교환술 ·························································································· 163
8. 백혈구성분채집술 ···························································································· 164
9. 치료적 백혈구성분채집술 ············································································ 165
10. 치료적 적혈구성분채집술 ·············································································· 166
11. 말초혈액조혈모세포채집술 ··········································································· 167
12. 태반제대혈 조혈모세포채집술 ····································································· 169
◆ 학습문제··············································································································· 172
􀁄 􀁐 􀁏 􀁕 􀁆 􀁏 􀁕 􀁔
07장 Human Leukocyte Antigen계
1. HLA System의 개요 ·························································································· 177
2. HLA 항원의 구조 ····························································································· 180
3. HLA 항체와 수혈 ······························································································ 183
4. HLA 항원과 장기이식 ······················································································ 184
5. HLA 항원과 친자감별 검사 ············································································· 185
학습문제···················································································································· 187
08장 수혈 부작용
1. 용혈성 수혈 부작용 ························································································ 191
2. 비용혈성 수혈 부작용 ···················································································· 193
3. 수혈 전파성 질환 ···························································································· 198
4. 수혈전파성질환 검사······················································································· 202
5. 수혈 부작용 관련 지침 사항 ··········································································· 205
◆ 학습문제··············································································································· 208
09장 수혈전 검사와 혈액관리
1. 수혈 전 검사의 목적과 과정 ·········································································· 213
2. 채혈 및 검체 관리 ·························································································· 213
3. ABO 및 Rh 혈액형 검사 ··············································································· 217
4. 항체선별 검사 ·································································································· 218
5. 항체동정 검사 ································································································ 220
6. 교차시험법 ······································································································ 228
7. 수혈혈액의 출고······························································································· 231
8. 수혈관찰 및 기록 ·························································································· 233
9. 출고된 혈액의 반납과 폐기············································································· 234
10. 혈액사용 지침·································································································· 237
11. 수혈을 위한 혈액제제의 선택·········································································· 239
12. 수혈의 기본 수칙····························································································· 243
13. 면역성 용혈성 빈혈 환자의 수혈 ·································································· 244
14. 분만전·후 검사 ······························································································· 247
􀁄 􀁐 􀁏 􀁕 􀁆 􀁏 􀁕 􀁔 10장 검사방법
1. ABO 혈액형 검사 ··························································································· 251
2. ABO 아형 검사 ······························································································ 265
3. 타액 검사 ·········································································································· 267
4. 혈청중의 A형 B형 물질의 검사 ····································································· 273
5. Rh 혈액형 검사 ································································································ 274
6. Rh 표현형 검사 ······························································································· 277
7. 약-D(Du)형 검사 ·························································································· 278
8. 부분D형 검사 ·································································································· 280
9. 항체 선별 및 동정검사 ··················································································· 283
10. 교차적합시험 ·································································································· 291
11. 항글로불린 검사 ····························································································· 306
12. 한랭 자가 흡착항체 검사 ··············································································· 316
13. 온난 자가 항체흡착 검사: ZZAP 법 ······························································ 318
14. 항체용출 검사 : Heat 법··················································································· 322
15. 항체용출 검사 : Ether법·················································································· 324
16. 항체해리 검사 : Chloroquine 법····································································· 325
17. 한랭 자가항체 역가 검사 ··············································································· 327
18. Rh 항체역가 검사 ··························································································· 328
19. 동종응집소 역가 검사 ······················································································ 329
20. 기타 혈액형 검사 ···························································································· 331
21. Donath-Landsteiner Test··············································································· 333
22. 약제 유발성 용혈성 검사 ··············································································· 334
23. 신생아 용혈성 질환 검사 ··············································································· 337
24. HLA Typing······································································································ 340
25. HLA Crossmatch······························································································ 346
26. HLA DR, DQ DNA Typing: PCR-SSO························································ 350
27. HLA antibody(PRA)························································································· 357
28. 혈소판 혈액성분채집술 ·················································································· 357
29. Buffycoat Bone marrow Collection······························································ 360
30. 제대혈·············································································································· 362
31. 조혈모세포 채집 및 처리·················································································· 364
32. Cryosupernatant······························································································· 373
􀁄 􀁐 􀁏 􀁕 􀁆 􀁏 􀁕 􀁔
11장 정도관리
1. 혈액은행 정도관리 개요··················································································· 387
2. Proficiency Test······························································································· 389
3. Critical Value 에 관한 처리 지침···································································· 390
4. 검사오류············································································································ 390
5. 검사지침서 ······································································································· 391
6. 시약···················································································································· 392
7. 기기 및 장비······································································································ 392
8. 기록 및 문서······································································································ 394
9. Procedure와 검사 ··························································································· 395
10. 수혈용 혈액의 출고··························································································· 397
11. 수혈 부작용········································································································ 398
12. 혈액 사용기준 ·································································································· 399
13. 성분혈액············································································································· 400
14. 헌혈····················································································································· 401
15. 헌혈자 검사········································································································ 402
16. 혈액성분채집술································································································· 403
17. 인력····················································································································· 404
18. 방사능 안정········································································································ 404
실전 100제 및 해설 ·································································································407
부록································································································································443
찾아보기·······················································································································487