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          Harrison's Principles of Internal Medicine, 20/e
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          출판사 McGraw-Hill
          저자 J. Larry Jameson, Anthony S. Fauci, Dennis L. Kasper, Stephen L. Hauser, Dan L. Longo, Joseph L
          출간일 2018-08-01
          ISBN 9781259834936
          핀형 Hardcover l 20판
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          Harrison's landmark 20th edition is your essential guide to mastering the complexity of modern medicine.

          With more than 68 years in publication, Harrison’s Principles of Internal Medicine is trusted by generations of students and clinicians to maintain the ideal balance between the scientific basis of signs and symptoms and the clinical management of the patient, ensuring you deliver the best, most accurate care possible. Harrison’s landmark 20th edition is the leading authority on applied pathophysiology and clinical medicine.




          Part 1: The Profession of Medicine

          1 The Practice of MedicineThe Editors
          2 Promoting Good HealthDonald M. Lloyd-Jones, Kathleen M. McKibbin
          3 Decision-Making in Clinical MedicineDaniel B. Mark, John B. Wong
          4 Screening and Prevention of DiseaseKatrina A. Armstrong, Gary J. Martin
          5 Health Care Systems in Developed CountriesRichard B. Saltman
          6 The Safety and Quality of Health CareDavid W. Bates
          7 Racial and Ethnic Disparities in Health CareJoseph R. Betancourt, Alexander R. Green
          8 Ethical Issues in Clinical Medicine Bernard Lo, Christine Grady
          9 Palliative and End-of-Life CareEzekiel J. Emanuel


          Part 2: Cardinal Manifestations and Presentation of Diseases

          Section 1: Pain

          10 Pain: Pathophysiology and ManagementJames P. Rathmell, Howard L. Fields
          11 Chest DiscomfortDavid A. Morrow
          12 Abdominal PainDanny O. Jacobs
          13 HeadachePeter J. Goadsby
          14 Back and Neck PainJohn W. Engstrom


          Section 2: Alterations in Body Temperature

          15 FeverCharles A. Dinarello, Reuven Porat
          16 Fever and RashElaine T. Kaye, Kenneth M. Kaye
          17 Fever of Unknown OriginChantal P. Bleeker-Rovers, Jos W. M. van der Meer


          Section 3: Nervous System Dysfunction

          18 SyncopeRoy Freeman
          19 Dizziness and VertigoMark F. Walker, Robert B. Daroff
          20 FatigueJeffrey M. Gelfand, Vanja C. Douglas
          21 Neurologic Causes of Weakness and ParalysisMichael J. Aminoff
          22 Numbness, Tingling, and Sensory LossMichael J. Aminoff
          23 Gait Disorders, Imbalance and Falls Jessica M. Baker, Lewis R. Sudarsky
          24 Confusion and DeliriumS. Andrew Josephson, Bruce L. Miller
          25 DementiaWilliam W. Seeley, Bruce L. Miller
          26 Aphasia, Memory Loss, Hemispatial Neglect, Frontal Syndromes and Other Cerebral DisordersM.-Marsel Mesulam
          27 Sleep DisordersThomas E. Scammell, Clifford B. Saper, Charles A. Czeisler


          Section 4: Disorders of Eyes, Ears, Nose, and Throat

          28 Disorders of the EyeJonathan C. Horton
          29 Disorders of Smell and Taste Richard L. Doty, Steven M. Bromley
          30 Disorders of HearingAnil K. Lalwani
          31 Sore Throat, Earache, and Upper Respiratory SymptomsMichael A. Rubin, Larry C. Ford, Ralph Gonzales
          32 Oral Manifestations of DiseaseSamuel C. Durso


          Section 5: Alterations in Circulatory and Respiratory Functions

          33 DyspneaRebecca M. Baron
          34 Cough Christopher H. Fanta
          35 HemoptysisAnna K. Brady, Patricia A. Kritek
          36 Hypoxia and CyanosisJoseph Loscalzo
          37 EdemaEugene Braunwald, Joseph Loscalzo
          38 Approach to the Patient with a Heart Murmur Patrick T. O'Gara, Joseph Loscalzo
          39 PalpitationsJoseph Loscalzo


          Section 6: Alterations in Gastrointestinal Function

          40 DysphagiaIkuo Hirano, Peter J. Kahrilas
          41 Nausea, Vomiting, and IndigestionWilliam L. Hasler
          42 Diarrhea and ConstipationMichael Camilleri, Joseph A. Murray
          43 Unintentional Weight LossJ. Larry Jameson
          44 Gastrointestinal BleedingLoren Laine
          45 JaundiceSavio John, Daniel S. Pratt
          46 Abdominal Swelling and AscitesKathleen E. Corey, Lawrence S. Friedman


          Section 7: Alterations in Renal and Urinary Tract Function

          47 Dysuria, Bladder Pain, and the Interstitial Cystitis/ Bladder Pain SyndromeJohn W. Warren
          48 Azotemia and Urinary Abnormalities David B. Mount
          49 Fluid and Electrolyte Disturbances David B. Mount
          50 Hypercalcemia and Hypocalcemia Sundeep Khosla
          51 Acidosis and AlkalosisThomas D. DuBose, Jr.


          Section 8: Alterations in the Skin

          52 Approach to the Patient with a Skin DisorderKim B. Yancey, Thomas J. Lawley
          53 Eczema, Psoriasis, Cutaneous Infections, Acne, and Other Common Skin DisordersLeslie P. Lawley, Calvin O. McCall, Thomas J. Lawley
          54 Skin Manifestations of Internal DiseaseJean L. Bolognia, Irwin M. Braverman
          55 Immunologically Mediated Skin Diseases Kim B. Yancey, Thomas J. Lawley
          56 Cutaneous Drug ReactionsRobert G. Micheletti, Misha Rosenbach, Bruce U. Wintroub, Kanade Shinkai
          57 Photosensitivity and Other Reactions to LightAlexander G. Marneros, David R. Bickers


          Section 9: Hematologic Alterations

          58 Interpreting Peripheral Blood Smears Dan L. Longo
          59 Anemia and PolycythemiaJohn W. Adamson, Dan L. Longo
          60 Disorders of Granulocytes and MonocytesSteven M. Holland, John I. Gallin
          61 Bleeding and ThrombosisBarbara A. Konkle
          62 Enlargement of Lymph Nodes and SpleenDan L. Longo


          Part 3: Pharmacology

          63 Principles of Clinical PharmacologyDan M. Roden
          64 Pharmacogenomics Dan M. Roden


          Part 4: Oncology and Hematology

          Section 1: Neoplastic Disorders

          65 Approach to the Patient with CancerDan L. Longo
          66 Prevention and Early Detection of Cancer Jennifer M. Croswell, Otis W. Brawley, Barnett S. Kramer
          67 Cancer GeneticsFred Bunz, Bert Vogelstein
          68 Cancer Cell BiologyJeffrey W. Clark, Dan L. Longo
          69 Principles of Cancer Treatment Edward A. Sausville, Dan L. Longo
          70 Infections in Patients with Cancer Robert W. Finberg
          71 Oncologic Emergencies Rasim Gucalp, Janice P. Dutcher
          72 Cancer of the SkinBrendan D. Curti, Sancy Leachman, Walter J. Urba
          73 Head and Neck Cancer Everett E. Vokes
          74 Neoplasms of the LungLeora Horn, Christine M. Lovly
          75 Breast CancerDaniel F. Hayes, Marc E. Lippman
          76 Upper Gastrointestinal Tract CancersRobert J. Mayer
          77 Lower Gastrointestinal Cancers Robert J. Mayer
          78 Tumors of the Liver and Biliary TreeJosep M. Llovet
          79 Pancreatic CancerDaniel D. Von Hoff
          80 Neuroendocrine Tumors of the Gastrointestinal Tract and PancreasRobert T. Jensen
          81 Renal Cell CarcinomaRobert J. Motzer
          82 Cancer of the Bladder and Urinary TractNoah M. Hahn
          83 Benign and Malignant Diseases of the ProstateHoward I. Scher, James A. Eastham
          84 Testicular CancerDavid J. Vaughn
          85 Gynecologic MalignanciesDavid Spriggs
          86 Primary and Metastatic Tumors of the Nervous SystemLisa M. DeAngelis, Patrick Y. Wen
          87 Soft Tissue and Bone Sarcomas and Bone Metastases Shreyaskumar R. Patel
          88 Carcinoma of Unknown PrimaryGauri R. Varadhachary, James L. Abbruzzese
          89 Paraneoplastic Syndromes: Endocrinologic/HematologicJ. Larry Jameson, Dan L. Longo
          90 Paraneoplastic Neurologic Syndromes and Autoimmune EncephalitisJosep Dalmau, Myrna R. Rosenfeld
          91 Late Consequences of Cancer and Its TreatmentCarl E. Freter, Dan L. Longo


          Section 2: Hematopoietic Disorders

          92 Hematopoietic Stem CellsDavid T. Scadden, Dan L. Longo
          93 Iron Deficiency and Other Hypoproliferative AnemiasJohn W. Adamson
          94 Disorders of HemoglobinEdward J. Benz, Jr.
          95 Megaloblastic AnemiasA. Victor Hoffbrand
          96 Hemolytic Anemias Lucio Luzzatto
          97 Anemia Due to Acute Blood LossDan L. Longo
          98 Bone Marrow Failure Syndromes Including Aplastic Anemia and MyelodysplasiaNeal S. Young
          99 Polycythemia Vera and Other Myeloproliferative NeoplasmsJerry L. Spivak
          100 Acute Myeloid LeukemiaWilliam Blum, Clara D. Bloomfield
          101 Chronic Myeloid LeukemiaHagop Kantarjian, Jorge Cortes
          102 Acute Lymphoid LeukemiaDieter Hoelzer
          103 Chronic Lymphocytic LeukemiaJennifer A. Woyach, John C. Byrd
          104 Non-Hodgkin's LymphomaCaron A. Jacobson, Dan L. Longo
          105 Hodgkin's Lymphoma Caron A. Jacobson, Dan L. Longo
          106 Less Common Hematologic MalignanciesAyalew Tefferi, Dan L. Longo
          107 Plasma Cell DisordersNikhil C. Munshi, Dan L. Longo, Kenneth C. Anderson
          108 AmyloidosisJohn L. Berk, Vaishali Sanchorawala
          109 Transfusion Biology and TherapyJeffery S. Dzieczkowski, Pierre Tiberghien, Kenneth C. Anderson
          110 Hematopoietic Cell TransplantationFrederick R. Appelbaum


          Section 3: Disorders of Hemostasis

          111 Disorders of Platelets and Vessel WallBarbara A. Konkle
          112 Coagulation DisordersValder R. Arruda, Katherine A. High
          113 Arterial and Venous ThrombosisJane E. Freedman, Joseph Loscalzo
          114 Antiplatelet, Anticoagulant, and Fibrinolytic DrugsJeffrey I. Weitz


          Part 5: Infectious Diseases

          Section 1: Basic Considerations in Infectious Diseases

          115 Approach to the Patient with an Infectious DiseaseNeeraj K. Surana, Dennis L. Kasper
          116 Molecular Mechanisms of Microbial Pathogenesis Gerald B. Pier
          117 Approach to the Acutely Ill Infected Febrile PatientTamar F. Barlam, Dennis L. Kasper
          118 Immunization Principles and Vaccine UseNancy Messonnier, Anne Schuchat, Lisa A. Jackson
          119 Health Recommendations for International TravelJay S. Keystone, Phyllis E. Kozarsky
          120 Climate Change and Infectious DiseaseAaron S. Bernstein


          Section 2: Clinical Syndromes: Community-Acquired Infections

          121 PneumoniaLionel A. Mandell, Richard G. Wunderink
          122 Lung AbscessRebecca M. Baron, Miriam Baron Barshak
          123 Infective EndocarditisAdolf W. Karchmer
          124 Infections of the Skin, Muscles, and Soft TissuesDennis L. Stevens
          125 Infectious ArthritisLawrence C. Madoff
          126 OsteomyelitisWerner Zimmerli
          127 Intraabdominal Infections and AbscessesMiriam Baron Barshak, Dennis L. Kasper
          128 Acute Infectious Diarrheal Diseases and Bacterial Food PoisoningRichelle C. Charles, Stephen B. Calderwood, Regina C. LaRocque
          129 Clostridium difficile Infection, Including Pseudomembranous ColitisDale N. Gerding, Stuart Johnson
          130 Urinary Tract Infections, Pyelonephritis, and ProstatitisKalpana Gupta, Barbara W. Trautner
          131 Sexually Transmitted Infections: Overview and Clinical ApproachJeanne M. Marrazzo, King K. Holmes
          132 EncephalitisKaren L. Roos, Kenneth L. Tyler
          133 Acute MeningitisKaren L. Roos, Kenneth L. Tyler
          134 Chronic and Recurrent MeningitisWalter J. Koroshetz, Michael R. Wilson, Avindra Nath
          135 Brain Abscess and EmpyemaKaren L. Roos, Kenneth L. Tyler
          136 Infectious Complications of BitesSandeep S. Jubbal, Florencia Pereyra, Lawrence C. Madoff


          Section 3: Clinical Syndromes: Health Care-Associated Infections

          137 Infections Acquired in Health Care FacilitiesRobert A. Weinstein
          138 Infections in Transplant RecipientsRobert W. Finberg, Joyce D. Fingeroth


          Section 4: Therapy for Bacterial Diseases

          139 Treatment and Prophylaxis of Bacterial InfectionsDavid C. Hooper, Erica S. Shenoy, Christy A. Varughese
          140 Bacterial Resistance to Antimicrobial AgentsDavid C. Hooper


          Section 5: Diseases Caused by Gram-Positive Bacteria

          141 Pneumococcal InfectionsDavid Goldblatt, Katherine L. O'Brien
          142 Staphylococcal InfectionsFranklin D. Lowy
          143 Streptococcal InfectionsMichael R. Wessels
          144 Enterococcal InfectionsCesar A. Arias, Barbara E. Murray
          145 Diphtheria and Other Corynebacterial InfectionsWilliam R. Bishai, John R. Murphy
          146 Listeria monocytogenes InfectionsElizabeth L. Hohmann, Daniel A. Portnoy
          147 TetanusC. Louise Thwaites, Lam Minh Yen
          148 BotulismAgam K. Rao, Susan Maslanka
          149 Gas Gangrene and Other Clostridial InfectionsAmy E. Bryant, Dennis L. Stevens


          Section 6: Diseases Caused by Gram-Negative Bacteria

          150 Meningococcal InfectionsAndrew J. Pollard
          151 Gonococcal InfectionsSanjay Ram, Peter A. Rice
          152 Haemophilus and Moraxella InfectionsTimothy F. Murphy
          153 Infections Due to the HACEK Group and Miscellaneous Gram-Negative BacteriaTamar F. Barlam, Dennis L. Kasper
          154 Legionella InfectionsVictor L. Yu, M. Luisa Pedro-Botet, Yusen E. Lin
          155 Pertussis and Other Bordetella InfectionsKarina A. Top, Scott A. Halperin
          156 Diseases Caused by Gram-Negative Enteric BacilliThomas A. Russo, James R. Johnson
          157 Acinetobacter InfectionsRossana Rosa, L. Silvia Munoz-Price
          158 Helicobacter pylori InfectionsJohn C. Atherton, Martin J. Blaser
          159 Infections Due to Pseudomonas, Burkholderia, and Stenotrophomonas SpeciesReuben Ramphal
          160 SalmonellosisDavid A. Pegues, Samuel I. Miller
          161 ShigellosisPhilippe J. Sansonetti, Jean Bergounioux
          162 Infections Due to Campylobacter and Related OrganismsBeth D. Kirkpatrick, Martin J. Blaser
          163 Cholera and Other VibriosesMatthew K. Waldor, Edward T. Ryan
          164 BrucellosisNicholas J. Beeching
          165 TularemiaJeannine M. Petersen, Paul S. Mead
          166 Plague and Other Yersinia InfectionsMichael B. Prentice
          167 Bartonella Infections, Including Cat-Scratch DiseaseMichael Giladi, Moshe Ephros
          168 DonovanosisNigel O'Farrell


          Section 7: Miscellaneous Bacterial Infections

          169 NocardiosisGregory A. Filice
          170 Actinomycosis Thomas A. Russo
          171 Whipple's DiseaseThomas A. Russo
          172 Infections Due to Mixed Anaerobic OrganismsNeeraj K. Surana, Dennis L. Kasper


          Section 8: Mycobacterial Diseases

          173 TuberculosisMario C. Raviglione
          174 LeprosyRobert H. Gelber
          175 Nontuberculous Mycobacterial InfectionsSteven M. Holland
          176 Antimycobacterial AgentsDivya Reddy, Max R. O'Donnell


          Section 9: Spirochetal Diseases

          177 SyphilisSheila A. Lukehart
          178 Endemic TreponematosesSheila A. Lukehart
          179 LeptospirosisJi'i F. P. Wagenaar, Marga G. A. Goris
          180 Relapsing FeverAlan G. Barbour
          181 Lyme BorreliosisAllen C. Steere


          Section 10: Diseases Caused by Rickettsiae, Mycoplasmas, and Chlamydiae

          182 Rickettsial DiseasesDavid H. Walker, J. Stephen Dumler, Lucas S. Blanton, Thomas J. Marrie
          183 Infections Due to Mycoplasmas R. Doug Hardy
          184 Chlamydial InfectionsCharlotte A. Gaydos, Thomas C. Quinn


          Section 11: Viral Diseases: General Considerations

          185 Medical VirologyFred Wang, Elliott Kieff
          186 Antiviral Chemotherapy, Excluding Antiretroviral DrugsLindsey R. Baden


          Section 12: Infections Due to DNA Viruses

          187 Herpes Simplex Virus InfectionsLawrence Corey
          188 Varicella-Zoster Virus InfectionsRichard J. Whitley
          189 Epstein-Barr Virus Infections, Including Infectious MononucleosisJeffrey I. Cohen
          190 Cytomegalovirus and Human Herpesvirus Types 6, 7, and 8 Camille Nelson Kotton, Martin S. Hirsch
          191 Molluscum Contagiosum, Monkeypox, and Other Poxvirus InfectionsFred Wang
          192 Parvovirus InfectionsKevin E. Brown
          193 Human Papillomavirus Infections Darron R. Brown, Aaron Ermel


          Section 13: Infections Due to DNA and RNA Respiratory Viruses

          194 Common Viral Respiratory Infections James E. Crowe, Jr.
          195 InfluenzaPeter F. Wright


          Section 14: Infections Due to Human Immunodeficiency Virus and Other Human Retroviruses

          196 The Human RetrovirusesDan L. Longo, Anthony S. Fauci
          197 Human Immunodeficiency Virus Disease: AIDS and Related DisordersAnthony S. Fauci, Gregory K. Folkers, H. Clifford Lane


          Section 15: Infections Due to RNA Viruses

          198 Viral GastroenteritisUmesh D. Parashar, Roger I. Glass
          199 Enterovirus, Parechovirus, and Reovirus InfectionsJeffrey I. Cohen
          200 Measles (Rubeola)Kaitlin Rainwater-Lovett, William J. Moss
          201 Rubella (German Measles)Laura A. Zimmerman, Susan E. Reef
          202 MumpsSteven A. Rubin
          203 Rabies and Other Rhabdovirus InfectionsAlan C. Jackson
          204 Arthropod-Borne and Rodent-Borne Virus InfectionsJens H. Kuhn, Rémi N. Charrel
          205 Ebolavirus and Marburgvirus InfectionsJens H. Kuhn


          Section 16: Fungal Infections

          206 Diagnosis and Treatment of Fungal InfectionsJohn E. Edwards, Jr.
          207 HistoplasmosisChadi A. Hage, L. Joseph Wheat
          208 CoccidioidomycosisNeil M. Ampel
          209 BlastomycosisS. Travis King, Rathel L. Nolan, III
          210 CryptococcosisArturo Casadevall
          211 CandidiasisJohn E. Edwards, Jr.
          212 AspergillosisDavid W. Denning
          213 MucormycosisBrad Spellberg, Ashraf S. Ibrahim
          214 Superficial Mycoses and Less Common Systemic MycosesCarol A. Kauffman
          215 Pneumocystis Infections Alison Morris, Henry Masur


          Section 17: Protozoal and Helminthic Infections: General Considerations

          216 Introduction to Parasitic Infections Sharon L. Reed, Charles E. Davis
          217 Agents Used to Treat Parasitic Infections Thomas A. Moore


          Section 18: Protozoal Infections

          218 Amebiasis and Infection with Free-Living AmebaeRosa M. Andrade, Sharon L. Reed
          219 MalariaNicholas J. White, Elizabeth A. Ashley
          220 BabesiosisEdouard Vannier, Peter J. Krause
          221 Leishmaniasis Shyam Sundar
          222 Chagas Disease and African Trypanosomiasis François Chappuis, Yves Jackson
          223 Toxoplasma InfectionsKami Kim
          224 Protozoal Intestinal Infections and Trichomoniasis Peter F. Weller


          Section 19: Helminthic Infections

          225 Introduction to Helminthic InfectionsPeter F. Weller
          226 Trichinellosis and Other Tissue Nematode InfectionsPeter F. Weller
          227 Intestinal Nematode InfectionsPeter F. Weller, Thomas B. Nutman
          228 Filarial and Related InfectionsThomas B. Nutman, Peter F. Weller
          229 Schistosomiasis and Other Trematode InfectionsBirgitte Jyding Vennervald
          230 Cestode InfectionsA. Clinton White, Jr., Peter F. Weller


          Part 6: Disorders of the Cardiovascular System

          Section 1: Introduction to Cardiovascular Disorders

          231 Approach to the Patient with Possible Cardiovascular DiseaseJoseph Loscalzo
          232 Basic Biology of the Cardiovascular SystemJoseph Loscalzo, Peter Libby, Calum A. MacRae
          233 Epidemiology of Cardiovascular DiseaseThomas A. Gaziano, J. Michael Gaziano


          Section 2: Diagnosis of Cardiovascular Disorders

          234 Physical Examination of the Cardiovascular SystemPatrick T. O'Gara, Joseph Loscalzo
          235 ElectrocardiographyAry L. Goldberger
          236 Noninvasive Cardiac Imaging: Echocardiography, Nuclear Cardiology, and Magnetic Resonance/Computed Tomography ImagingMarcelo F. Di Carli, Raymond Y. Kwong, Scott D. Solomon
          237 Diagnostic Cardiac Catheterization and Coronary AngiographyJane A. Leopold, David P. Faxon


          Section 3: Disorders of Rhythm

          238 Principles of ElectrophysiologyDavid D. Spragg, Gordon F. Tomaselli
          239 The Bradyarrhythmias: Disorders of the Sinoatrial NodeDavid D. Spragg, Gordon F. Tomaselli
          240 The Bradyarrhythmias: Disorders of the Atrioventricular NodeDavid D. Spragg, Gordon F. Tomaselli
          241 Approach to Supraventricular TachyarrhythmiasGregory F. Michaud, William G. Stevenson
          242 Physiologic and Non-physiologic Sinus Tachycardia Gregory F. Michaud, William G. Stevenson
          243 Focal Atrial Tachycardia Gregory F. Michaud, William G. Stevenson
          244 Paroxysmal Supraventricular TachycardiasGregory F. Michaud, William G. Stevenson
          245 Common Atrial Flutter, Macroreentrant and Multifocal Atrial TachycardiasGregory F. Michaud, William G. Stevenson
          246 Atrial FibrillationGregory F. Michaud, William G. Stevenson
          247 Approach to Ventricular Arrhythmias Roy M. John, William G. Stevenson
          248 Premature Ventricular Beats, Non-sustained Ventricular Tachycardia, and Idioventricular Rhythm Roy M. John, William G. Stevenson
          249 Sustained Ventricular Tachycardia William G. Stevenson, Roy M. John
          250 Polymorphic Ventricular Tachycardia and Ventricular FibrillationWilliam G. Stevenson, Roy M. John
          251 Electrical Storm and Incessant VTWilliam G. Stevenson, Roy M. John


          Section 4: Disorders of the Heart

          252 Heart Failure: Pathophysiology and DiagnosisDouglas L. Mann, Murali Chakinala
          253 Heart Failure: ManagementMandeep R. Mehra
          254 Cardiomyopathy and MyocarditisNeal K. Lakdawala, Lynne Warner Stevenson, Joseph Loscalzo
          255 Cardiac Transplantation and Prolonged Assisted Circulation Mandeep R. Mehra
          256 Aortic Valve DiseasePatrick T. O'Gara, Joseph Loscalzo
          257 Aortic Regurgitation Patrick T. O'Gara, Joseph Loscalzo
          258 Mitral StenosisPatrick T. O'Gara, Joseph Loscalzo
          259 Mitral RegurgitationPatrick T. O'Gara, Joseph Loscalzo
          260 Mitral Valve ProlapsePatrick T. O'Gara, Joseph Loscalzo
          261 Tricuspid Valve DiseasePatrick T. O'Gara, Joseph Loscalzo
          262 Pulmonic Valve DiseasePatrick T. O'Gara, Joseph Loscalzo
          263 Multiple and Mixed Valvular Heart DiseasePatrick T. O'Gara, Joseph Loscalzo
          264 Congenital Heart Disease in the AdultAnne Marie Valente, Michael J. Landzberg
          265 Pericardial DiseaseEugene Braunwald
          266 Atrial Myxoma and Other Cardiac TumorsEric H. Awtry


          Section 5: Coronary and Peripheral Vascular Disease

          267 Ischemic Heart DiseaseElliott Antman, Joseph Loscalzo
          268 Non-ST-Segment Elevation Acute Coronary Syndrome (Non-ST-Segment Elevation Myocardial Infarction and Unstable Angina)Robert P. Giugliano, Christopher P. Cannon, Eugene Braunwald
          269 ST-Segment Elevation Myocardial InfarctionElliott M. Antman, Joseph Loscalzo
          270 Percutaneous Coronary Interventions and Other Interventional ProceduresDavid P. Faxon, Deepak L. Bhatt
          271 Hypertensive Vascular DiseaseTheodore A. Kotchen
          272 Renovascular DiseaseStephen C. Textor
          273 Deep Venous Thrombosis and Pulmonary ThromboembolismSamuel Z. Goldhaber
          274 Diseases of the AortaMark A. Creager, Joseph Loscalzo
          275 Arterial Diseases of the ExtremitiesMark A. Creager, Joseph Loscalzo
          276 Chronic Venous Disease and Lymphedema Mark A. Creager, Joseph Loscalzo
          277 Pulmonary HypertensionAaron B. Waxman, Joseph Loscalzo


          Part 7: Disorders of the Respiratory System

          Section 1: Diagnosis of Respiratory Disorders

          278 Approach to the Patient with Disease of the Respiratory SystemPatricia A. Kritek, Bruce D. Levy
          279 Disturbances of Respiratory FunctionEdward T. Naureckas, Julian Solway
          280 Diagnostic Procedures in Respiratory DiseaseAnne L. Fuhlbrigge, Augustine M.K. Choi 


          Section 2: Diseases of the Respiratory System

          281 AsthmaPeter J. Barnes
          282 Hypersensitivity Pneumonitis and Pulmonary Infiltrates with Eosinophilia Praveen Akuthota, Michael E. Wechsler


          Introducing the Landmark Twentieth Edition of the Global Icon of Internal Medicine

          The definitive guide to internal medicine is more essential than ever with the latest in disease mechanisms, updated clinical trial results and recommended guidelines, state-of-the art radiographic images, therapeutic approaches and specific treatments, hundreds of demonstrative full-color drawings, and practical clinical decision trees and algorithms

          Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine, Harrison's Principles of Internal Medicine gives you the informational foundation you need to provide the best patient care possible.

          Essential for practice and education, the landmark 20th Edition features:

          • Thoroughly revised content―covering the many new breakthroughs and advances in clinical medicine that have occurred since the last edition of Harrison's. Chapters on acute and chronic hepatitis, management of diabetes, immune-based therapies in cancer, multiple sclerosis, cardiovascular disease, HIV, and many more, deliver the very latest information on disease mechanisms, diagnostic options, and the specific treatment guidance you need to provide optimal patient care.
          • State-of-the-art coverage of disease mechanisms: Harrison's focuses on pathophysiology with rigor, and with the goal of linking disease mechanisms to treatments. Improved understanding of how diseases develop and progress not only promotes better decision-making and higher value care, but also makes for fascinating reading and improved retention. Harrison's summarizes important new basic science developments, such as the role of mitochondria in programmed and necrotic cell death, the immune system's role in cancer development and treatment, the impact of telomere shortening in the aging and disease processes, and the role of the microbiome in health and disease. Understanding the role of inflammation in cardiovascular disease, the precise mechanisms of immune deficiency in HIV/AIDS, prions and misfolded proteins in neurodegenerative diseases, and obesity as a predisposition to diabetes are just a few examples of how this edition provides essential pathophysiology information for health professionals.
          • All-new sections covering a wide range of new and emerging areas of vital interest to all healthcare professionals. New sections include: Sex and Gender-based Issues in Medicine; Obesity, Diabetes Mellitus, and Metabolic Syndrome; and Consultative Medicine― Plus, a new Part covering cutting-edge topics in research and clinical medicine includes great new chapters on the role of Epigenetics in Health and Disease, Behavioral Strategies to Improve Health, Genomics and Infectious Diseases, Emerging Neuro-Therapeutic Technologies, and Telomere Function in Health and Disease, and Network System Medicine.
          • Important and timely new chapters―such as Promoting Good Health, LGBT Health, Systems of Healthcare, Approach to Medical Consultation, Pharmacogenomics, Antimicrobial Resistance, Worldwide Changes in Patterns of Infectious Diseases, Neuromyelitis Optica, and more―offer the very latest, definitive perspectives on must-know topics in medical education and practice. 
          • Updated clinical guidelines, expert opinions, and treatment approaches from world-renowned editors and authors contribute to the accuracy and immediacy of the text material and present a clear blueprint for optimizing patient outcomes.
          • End-of-chapter suggested readings reinforce the text material and provide a robust platform for further study and research.

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